RAMAN SPECTRA BASED METHOD OF IDENTIFYING THE SUBTYPE OF ACUTE LYMPHOBLASTIC LEUKEMIA WITH KMT2A GENE REARRANGEMENT

RAMAN SPECTRA BASED METHOD OF IDENTIFYING THE SUBTYPE OF ACUTE LYMPHOBLASTIC LEUKEMIA WITH KMT2A GENE REARRANGEMENT

A method of identifying the ALL molecular subtype with rearrangements within the KMT2A gene was disclosed, which consists in measuring the ratio of the intensity of the Raman 1040/1008 cm-1 Raman bands in leukemia cells (lymphoblasts) isolated from the peripheral blood (when blastosis >90%) or bo...

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Hauptverfasser: Z bczy ska, Marta, Nowakowska, Anna, Leszczenko, Patrycja, Pastorczak, Agata, Bara ska, Ma gorzata, M ynarski, Wojciech, Majzner, Katarzyna, Jakubowska, Justyna, Ostrowska, Kinga
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Zusammenfassung:A method of identifying the ALL molecular subtype with rearrangements within the KMT2A gene was disclosed, which consists in measuring the ratio of the intensity of the Raman 1040/1008 cm-1 Raman bands in leukemia cells (lymphoblasts) isolated from the peripheral blood (when blastosis >90%) or bone marrow of patients during the diagnosis of acute lymphoblastic leukemia, and fixed with an aldehyde reagent.