FGF21 MUTANTS AND USES THEREOF

The invention provides nucleic acid molecules encoding FGF21 mutant polypeptides, FGF21 mutant polypeptides, pharmaceutical compositions comprising FGF21 mutant polypeptides, and methods for treating metabolic disorders using such nucleic acids, polypeptides, or pharmaceutical compositions.

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Bibliographische Detailangaben
Hauptverfasser: ELLISON, Murielle Marie, LI, Yue-Sheng, XU, Jing, SUN, Jeonghoon, BELOUSKI, Edward John, HAMBURGER, Agnes Eva, MICHAELS, Mark Leo, HECHT, Randy Ira
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The invention provides nucleic acid molecules encoding FGF21 mutant polypeptides, FGF21 mutant polypeptides, pharmaceutical compositions comprising FGF21 mutant polypeptides, and methods for treating metabolic disorders using such nucleic acids, polypeptides, or pharmaceutical compositions.