CELLS SENSITIVE TO BOTULINUM TOXIN INTO WHICH SPECIFIC GENE HAS BEEN INSERTED BY LENTIVIRUS

The present invention relates to cells for measuring botulinum toxin activity overexpressing SEPTIN2 or Thioredoxin (TXN), and to a method for measuring botulinum toxin activity, the method comprising the steps of: treating the cells for measuring botulinum toxin activity with botulinum toxin and cu...

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Bibliographische Detailangaben
Hauptverfasser:	JANG, Sung Su, LIM, Il Ho, LEE, Hak Sup, AHN, Yong Shik, CHOI, Doo Jin
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to cells for measuring botulinum toxin activity overexpressing SEPTIN2 or Thioredoxin (TXN), and to a method for measuring botulinum toxin activity, the method comprising the steps of: treating the cells for measuring botulinum toxin activity with botulinum toxin and culturing the cells; lysing the cultured cells and collecting a cell lysate; and measuring the amount of SNAP-25 cleavage products in the cell lysate.