AGONISTIC CD28 ANTIGEN BINDING MOLECULES TARGETING EPCAM

AGONISTIC CD28 ANTIGEN BINDING MOLECULES TARGETING EPCAM

The present invention relates to bispecific agonistic CD28 antigen binding molecules characterized by monovalent binding to CD28 comprising new humanized EpCAM antibodies, methods for their production, pharmaceutical compositions containing these antibodies, and methods of using the same.

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Bibliographische Detailangaben
Hauptverfasser: WEINZIERL, Tina, SAM, Johannes, GEORGES, Guy, HOFER, Thomas, KLEIN, Christian, UMAÑA, Pablo, GASSER, Stephan, MOESSNER, Ekkehard, THOM, Jenny Tosca
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:The present invention relates to bispecific agonistic CD28 antigen binding molecules characterized by monovalent binding to CD28 comprising new humanized EpCAM antibodies, methods for their production, pharmaceutical compositions containing these antibodies, and methods of using the same.