HUMAN FIBROBLAST GROWTH FACTOR 1 (FGF-1) MUTEINS, THEIR DIMERS AND USES

The present invention relates to human fibroblast growth factor (FGF-1) muteins having decreased mitogenicity, dimers of human FGF-1 muteins, as well as such human FGF-1 muteins and dimers of such muteins for use in reducing blood glucose level, particularly for use in the treatment of diabetes.

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: JANISZEWSKI, Micha Mieczys aw, ZAKRZEWSKA, Ma gorzata Urszula, KROWARSCH, Daniel Rafa, BUDA, Pawe, DRZAZGA, Ewa, CZYREK, Aleksandra Anna, PIECZYKOLAN, Jerzy Szczepan, BAZYD O-GUZENDA, Katarzyna, WIECZOREK, Maciej, OTLEWSKI, Jacek Józef
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present invention relates to human fibroblast growth factor (FGF-1) muteins having decreased mitogenicity, dimers of human FGF-1 muteins, as well as such human FGF-1 muteins and dimers of such muteins for use in reducing blood glucose level, particularly for use in the treatment of diabetes.