HUMAN FIBROBLAST GROWTH FACTOR 1 (FGF-1) MUTEINS, THEIR DIMERS AND USES

HUMAN FIBROBLAST GROWTH FACTOR 1 (FGF-1) MUTEINS, THEIR DIMERS AND USES

The present invention relates to human fibroblast growth factor (FGF-1) muteins having decreased mitogenicity, dimers of human FGF-1 muteins, as well as such human FGF-1 muteins and dimers of such muteins for use in reducing blood glucose level, particularly for use in the treatment of diabetes.

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Bibliographische Detailangaben
Hauptverfasser: KROWARSCH, Daniel Rafal, ZAKRZEWSKA, Malgorzata Urszula, JANISZEWSKI, Michal Mieczyslaw, DRZAZGA, Ewa, CZYREK, Aleksandra Anna, PIECZYKOLAN, Jerzy Szczepan, BAZYDLO-GUZENDA, Katarzyna, BUDA, Pawel, WIECZOREK, Maciej, OTLEWSKI, Jacek Józef
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:The present invention relates to human fibroblast growth factor (FGF-1) muteins having decreased mitogenicity, dimers of human FGF-1 muteins, as well as such human FGF-1 muteins and dimers of such muteins for use in reducing blood glucose level, particularly for use in the treatment of diabetes.