TRIAZOLO-PYRIMIDINE ANALOGUES FOR TREATING DISEASES CONNECTED TO THE INHIBITON OF WERNER SYNDROME RECQ HELICASE (WRN)
The present invention provides a compound, or a pharmaceutically acceptable salt thereof, of formula (I):wherein R1, R2, R3, R4, R5, R26, R27, y, R, M, W, L, V, T, Y, J, K and A are as described herein, therapeutic uses of said compounds, uses of said compounds as research chemicals, a pharmaceutica...
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| creator | ZHANG, Sisi MOEBITZ, Henrik NOCITO, Sandro GOGNIAT, Geoffrey GONG, Wanben SOTO, Jessica HOLZER, Philipp SCHOEPFER, Joseph ZECRI, Frédéric BORDAS, Vincent FUREGATI, Markus LIMAM, Fatma YU, Huangchao YAO, Shuping STRANG, Ross HAMON, Jacques BRUN, Jvan SCHMIEDEBERG, Niko DECKER, Andrea HINRICHS, Juergen Hans-Hermann PLATTNER, Simone |
| description | The present invention provides a compound, or a pharmaceutically acceptable salt thereof, of formula (I):wherein R1, R2, R3, R4, R5, R26, R27, y, R, M, W, L, V, T, Y, J, K and A are as described herein, therapeutic uses of said compounds, uses of said compounds as research chemicals, a pharmaceutical composition and combinations comprising said compounds, and methods for manufacturing the compounds of the invention. |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | TRIAZOLO-PYRIMIDINE ANALOGUES FOR TREATING DISEASES CONNECTED TO THE INHIBITON OF WERNER SYNDROME RECQ HELICASE (WRN) |
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