PROCESS FOR THE SYNTHESIS OF SUBSTITUTED TETRAHYDROFURAN MODULATORS OF SODIUM CHANNELS

PROCESS FOR THE SYNTHESIS OF SUBSTITUTED TETRAHYDROFURAN MODULATORS OF SODIUM CHANNELS

Provided in this application is a process for making Compound I (I) and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels. Processes for making various intermediate products, and suitable salts thereof, are also provided.

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Bibliographische Detailangaben
Hauptverfasser: MCTIERNAN, Andrew, SHANAHAN, Stephen, O'DONNELL, Michael Edward, CHANGI, Shujauddin M, WIJETHUNGA, Tharanga K, EMER, Enrico, LEWANDOWSKI, Berenice L, DAVIS, Christopher John, PORTELA, Mireia Sidera, PANESAR, Maninder, EVERITT, Simon Robert, HARRISON, Cristian, SOUSA, Bruno Artur
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Provided in this application is a process for making Compound I (I) and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels. Processes for making various intermediate products, and suitable salts thereof, are also provided.