SUBSTITUTED TETRAHYDROFURAN ANALOGS AS MODULATORS OF SODIUM CHANNELS

Compounds of formula I, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable sal...

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Hauptverfasser:	SKERRATT, Sarah, CARVALHO MEIRELES, Lidio Marx, SHAW, David Matthew, PONTILLO, Joseph, FRAYSSE, Damien, GALAN, Bhairavi, MUI, James Jun Bon, STAMOS, Dean, CHUDYK, Ewa Iwona, GEDDIS, Stephen Michael, PULLIN, Robert, KNEGTEL, Ronald Marcellus, SCHMIDT, Yvonne, AUSTIN, James Robert, JACQUES, Reece, NORTH, Kiri, ETXEBARRIA JARDI, Gorka, HURLEY, Dennis James, HADIDA RUAH, Sara S, NEUBERT, Timothy Donald, BECK, Elizabeth Mary, STORCK, Pierre-Henri, THOMSON, Stephen Andrew, VIRANI, Anisa Nizarali, AHMAD, Nadia M, KINTZER, Alexander, DURRANT, Steven John, PINDER, Joanne Louise, WRAY, Christopher, SOUSA, Bruno Artur
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Compounds of formula I, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.