VERY EFFICIENT PROCESS FOR THE PREPARATION OF AGOMELATINE

The present invention is directed to a very efficient process for the preparation of Agomelatine wherein the intermediate 7-methoxynaphtalenacetonitrile is reduced by Lithium Aluminium hydride in presence of a Lewis acid.

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Bibliographische Detailangaben
Hauptverfasser: Motterle, Riccardo, Defilippo, Christian
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention is directed to a very efficient process for the preparation of Agomelatine wherein the intermediate 7-methoxynaphtalenacetonitrile is reduced by Lithium Aluminium hydride in presence of a Lewis acid.