METHODS FOR DELIVERING GENOME EDITING MOLECULES TO THE NUCLEUS OR CYTOSOL OF A CELL AND USES THEREOF

The present disclosure provides methods for delivering one or more payloads (e.g., gene-editing pay load) to a cell, wherein the method comprises passing a cell suspension comprising the cell and the pay load through one or more constrictions, wherein the one or more constrictions deform the cell, t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	SIKORA HANSON, Jacquelyn L, TADIN-STRAPPS, Marija
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present disclosure provides methods for delivering one or more payloads (e.g., gene-editing pay load) to a cell, wherein the method comprises passing a cell suspension comprising the cell and the pay load through one or more constrictions, wherein the one or more constrictions deform the cell, thereby causing a perturbation of the cell such that the one or more pay loads enters the cell.