DIGITAL SELECTION OF VISCOSITY REDUCING EXCIPIENTS FOR PROTEIN FORMULATIONS

Method for selecting at least one viscosity changing excipient for a formulation containing at least one unknown protein via a computer includes providing a data set that describes the viscosity of several known formulations containing at least one protein and optionally at least one viscosity changing excipient; generating representations of at least one excipient; using a Machine Learning Model executed on the computer to recognize patterns in the data set to evaluate the viscosity changing effect of the viscosity changing excipient to a new formulation containing at least one unknown protein by applying the recognized patterns on provided data of the unknown protein; selecting the at least one excipient according to an acquisition criterion and applying the excipient to the unknown protein, wherein the provided data of the at least one unknown protein describe the viscosity of a protein composition containing the at least one unknown protein.