IMIDAZO[1,2-B]PYRIDAZINE BASED TRICYCLIC COMPOUNDS AS INHIBITORS OF HASPIN AND THERAPEUTIC USES THEREOF

IMIDAZO[1,2-B]PYRIDAZINE BASED TRICYCLIC COMPOUNDS AS INHIBITORS OF HASPIN AND THERAPEUTIC USES THEREOF

The present invention relates to a group of compounds with a tricyclic core based on imidazo[1,2-b]pyridazine of formula (I):which are inhibitors of HASPIN, whose activity is required for the proliferation of certain tumoral cells, so the compounds of the invention are useful for the prevention and/...

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Bibliographische Detailangaben
Hauptverfasser: BLANCO APARICIO, Carmen, PASTOR FERNÁNDEZ, Joaquín, RODRÍGUEZ ARÍSTEGUI, Sonsoles, CEBRIÁ GÓMEZ, Antonio, GÓMEZ DE LA OLIVA, Cristina Ana, ALBARRÁN SANTIÑO, María Isabel, MALUMBRES MARTÍNEZ, Marcos, GARCÍA GARCÍA, Ana Belén, MARTÍNEZ GONZÁLEZ, Sonia
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention relates to a group of compounds with a tricyclic core based on imidazo[1,2-b]pyridazine of formula (I):which are inhibitors of HASPIN, whose activity is required for the proliferation of certain tumoral cells, so the compounds of the invention are useful for the prevention and/or treatment of cancer.