NEW 5,6,7,8-TETRAHYDROPYRIDO[4',3':4,5] THIENO[2,3-D]PYRIMIDIN-4(3H)-ONE DERIVATIVES AS SIGMA LIGANDS

NEW 5,6,7,8-TETRAHYDROPYRIDO[4',3':4,5] THIENO[2,3-D]PYRIMIDIN-4(3H)-ONE DERIVATIVES AS SIGMA LIGANDS

The present invention relates to new 5,6,7,8-tetrahydropyrido[4′,3′:4,5]thieno[2,3d] pyrimidin-4(3H)-one derivatives as sigma ligands having a great affinity for sigma receptors, especially sigma-1 (σ1), as well as to the process for the preparation thereof, to compositions comprising them, and to t...

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Bibliographische Detailangaben
Hauptverfasser: DÍAZ-FERNÁNDEZ, Jose Luis, CHRISTMANN, Ute
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention relates to new 5,6,7,8-tetrahydropyrido[4′,3′:4,5]thieno[2,3d] pyrimidin-4(3H)-one derivatives as sigma ligands having a great affinity for sigma receptors, especially sigma-1 (σ1), as well as to the process for the preparation thereof, to compositions comprising them, and to their use as medicaments.