COMPOUND OR SALT THEREOF, AND ANTIBODY OBTAINED USING SAME
The present invention provides a technique that controls a bonding ratio of an antibody and a modifying group within a desired range. More specifically, the present invention provides a compound or salt thereof represented by the following formula (I):whereinX indicates a leaving group,Y indicates a...
Gespeichert in:
Hauptverfasser: | , , , , , |
---|---|
Format: | Patent |
Sprache: | eng ; fre ; ger |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | The present invention provides a technique that controls a bonding ratio of an antibody and a modifying group within a desired range. More specifically, the present invention provides a compound or salt thereof represented by the following formula (I):whereinX indicates a leaving group,Y indicates an affinity peptide having a binding region in a CH2 domain in an immunoglobulin unit comprising two heavy chains and two light chains,M indicates a trivalent group linking the carbon atom in C=O adjacent to M and the carbon atom in C=W via a main chain portion consisting of 3 to 5 carbon atoms,O indicates an oxygen atom,S indicates a sulfur atom,W indicates an oxygen atom or a sulfur atom,N3 indicates an azide group,La indicates a bond or a divalent group, andLb indicates a bond or a divalent group; and antibodies or salts thereof which can be prepared using such a compound or salt thereof. |
---|