METHODS AND COMPOSITIONS FOR THE DELIVERY OF RETROVIRAL PARTICLES

The present disclosure provides methods and compositions for modifying lymphocytes, for example T cells and/or NK cells, for example in vivo. The disclosed compositions can include replication incompetent recombinant retroviral particles (RIPs), formulations thereof, and administration of RIP formul...

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Bibliographische Detailangaben
Hauptverfasser:	KERKAR, Sidharth, KUNDU, Anirban, FROST, Gregory Ian, SCHREIBER, Gregory, HENKELMAN, John R., III, VIGANT, Frederic
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present disclosure provides methods and compositions for modifying lymphocytes, for example T cells and/or NK cells, for example in vivo. The disclosed compositions can include replication incompetent recombinant retroviral particles (RIPs), formulations thereof, and administration of RIP formulations to a subject. Furthermore, the compositions can include chemokines, including chemokines delivered and/or associated with RIPs.