DIHYDROERGOTAMINE DRY POWDER FORMULATIONS AND METHODS OF USE

The present disclosure relates to dry powder formulations comprising respirable dry particles that comprise 1) dihydroergotamine (DHE) or a salt, hydrate, or polymorph thereof, 2) a monovalent metal cation salt, and 3) one or more excipients; and also relates to methods of using the dry powder for t...

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Bibliographische Detailangaben
Hauptverfasser: BERGSON, Hillary, T, STOLZ, Eric, C, GONZALEZ NELSON, Aaron, C, PERRY, Jason, M, CURRAN, Aidan, K, HANSON, Dayna, F
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present disclosure relates to dry powder formulations comprising respirable dry particles that comprise 1) dihydroergotamine (DHE) or a salt, hydrate, or polymorph thereof, 2) a monovalent metal cation salt, and 3) one or more excipients; and also relates to methods of using the dry powder for the treatment of a migraine, headache, or a symptom thereof, methods of making the dry powder, and receptacles and devices containing the dry powder.