METHODS AND THERAPEUTIC COMBINATIONS FOR TREATING IDIOPATHIC INTRACRANIAL HYPERTENSION AND CLUSTER HEADACHES

Methods and therapeutic combinations are provided for treating idiopathic intracranial hypertension (IIH) and cluster headache, comprising administering a somatostatin mimetic such as octreotide formulated for direct nose-to-brain administration, and a carbonic anhydrase inhibitor such as topiramate...

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Hauptverfasser: BEVEC, Dorian, PRICE, Fredric, D, FRANKEL, Barry, R, WASIEWSKI, Warren
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Methods and therapeutic combinations are provided for treating idiopathic intracranial hypertension (IIH) and cluster headache, comprising administering a somatostatin mimetic such as octreotide formulated for direct nose-to-brain administration, and a carbonic anhydrase inhibitor such as topiramate or acetazolamide, at a dose level and/or dosing regimen lower than effective when administered alone.