ANTI-TRPV6 MONOCLONAL ANTIBODY AND APPLICATION THEREOF

A segment of characteristic polypeptide antigen of a TRPV6 protein is selected to immunize mice and then screening is performed to obtain hybridoma cell lines 12CT 9.5.1, 16CT 18.1.1.2 and 16CT 4.1.1.2. The series of cells can secrete monoclonal antibodies against TRPV6 and can specifically recogniz...

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Bibliographische Detailangaben
Hauptverfasser:	WANG, Zhongbo, WANG, Wei, TAN, Wei, HUANG, Baohua Robert
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Zusammenfassung:	A segment of characteristic polypeptide antigen of a TRPV6 protein is selected to immunize mice and then screening is performed to obtain hybridoma cell lines 12CT 9.5.1, 16CT 18.1.1.2 and 16CT 4.1.1.2. The series of cells can secrete monoclonal antibodies against TRPV6 and can specifically recognize the TRPV6 protein and tumor tissue. The series of antibodies can measure the level of TRPV6 in cells in an artificial or automated manner by means of immunohistochemistry (IHC), enzyme-linked immunosorbent assay (ELISA), immunofluorescence (IF), chemiluminescence (CLA), immunoturbidimetric (TIA), or western blot, are thus used in a method for diagnosing tumor tissue, and relate to the field of biological detection.