METHOD AND DEVICE FOR SIMULATING THE EVOLUTION OF GASTRIC PH FOR IN VITRO DISSOLUTION AND RELEASE TESTS ON PHARMACEUTICAL FORMULATIONS

The invention relates to a method and a device for controlling pH which allows, by means of two solutions (one acidic and one basic), an accurate control of a third buffer solution in which dissolution and release of pharmaceutical formulations for oral administration are being tested. The concerned...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	IANNONE, Marco, CACCAVO, Diego, LAMBERTI, Gaetano
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The invention relates to a method and a device for controlling pH which allows, by means of two solutions (one acidic and one basic), an accurate control of a third buffer solution in which dissolution and release of pharmaceutical formulations for oral administration are being tested. The concerned device, in addition, allows the simulation of the physiological pH conditions that a pharmaceutical formulation will encounter along the human gastrointestinal tract.