AZOLO COMPOUNDS FOR TREATMENT OF FIBROTIC DISEASES
The present invention relates to an azolo compound of Formula Ifor use in the treatment of fibrosis, wherein the azolo compounds normalizes collagen I mRNA-levels of TGFβ-activated fibroblasts and reverses collagen production to the normal levels that are seen in fibroblasts that are not stimulated....
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| creator | VOSS, Edgar HASENFUSS, Gerd NYAMSUREN, Gunsmaa TIETZE, Lutz Friedjahn MOTHUKU, Shyam Sundar ZEISBERG, Michael |
| description | The present invention relates to an azolo compound of Formula Ifor use in the treatment of fibrosis, wherein the azolo compounds normalizes collagen I mRNA-levels of TGFβ-activated fibroblasts and reverses collagen production to the normal levels that are seen in fibroblasts that are not stimulated. |
| format | Patent |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | AZOLO COMPOUNDS FOR TREATMENT OF FIBROTIC DISEASES |
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