IMPROVED OLIGONUCLEOTIDE SYNTHESIS SUPPRESSING DEPURINATION

An improved protocol for the synthesis of oligonucleotides is provided. A liquid composition for the cleavage of a di(p-methoxyphenyl)phenylmethyl protecting group from a hydroxyl group and the use thereof in chemical synthesis of oligonucleotides is disclosed.

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Bibliographische Detailangaben
Hauptverfasser:	Eisenhuth, Ralf, Samson, Daniel, Haug, Karl Rüdiger, Berthelmann, Arne, Creusen, Guido
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY SUGARS
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Beschreibung
Zusammenfassung:	An improved protocol for the synthesis of oligonucleotides is provided. A liquid composition for the cleavage of a di(p-methoxyphenyl)phenylmethyl protecting group from a hydroxyl group and the use thereof in chemical synthesis of oligonucleotides is disclosed.