METHODS, ANTIBODIES OR ANTIGEN BINDING FRAGMENTS AND OTHER TOOLS FOR DETERMINING TARGET MOLECULES

The invention relates to a method for determining a target molecule in a sample. Also, the invention relates to a Förster resonance energy transfer (FRET, fluorescence resonance energy transfer) pair, recombinant antibodies, or antigen binding fragments thereof that bind Staphylococcus aureus Entero...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: JYLHÄ, Sirpa, NEVANEN, Tarja, AROLA, Henri
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The invention relates to a method for determining a target molecule in a sample. Also, the invention relates to a Förster resonance energy transfer (FRET, fluorescence resonance energy transfer) pair, recombinant antibodies, or antigen binding fragments thereof that bind Staphylococcus aureus Enterotoxin A and a test kit comprising the FRET pair, antibody or antigen binding fragment. Furthermore, the present invention relates to an isolated nucleic acid molecule comprising a nucleotide sequence that encodes the recombinant antibody or antigen binding fragment, and an expression vector comprising said nucleic acid molecule. Still, the invention relates to use of the FRET pair or the recombinant antibody or an antigen binding fragment thereof for determining a target molecule such as Staphylococcus aureus Enterotoxin A in a sample. And still, the invention relates to a method of producing the antibody or antigen binding fragment.