ADENO-ASSOCIATED VIRUS VECTOR FORMULATIONS AND METHODS

Provided herein is a stable formulation comprising a recombinant adeno-associated virus (rAAV) particle. The rAAV particle comprises an AAV9 capsid protein. Also provided herein are methods of producing the stable formulation and methods for reducing rAAV genome release from rAAV particles.

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Bibliographische Detailangaben
Hauptverfasser: ZHANG, Yu, MARSHALL, Tristan, DEPAZ, Roberto, BEE, Jared
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Provided herein is a stable formulation comprising a recombinant adeno-associated virus (rAAV) particle. The rAAV particle comprises an AAV9 capsid protein. Also provided herein are methods of producing the stable formulation and methods for reducing rAAV genome release from rAAV particles.