ENZYME VARIANTS AND USES THEREOF

The present disclosure relates generally to a polypeptide having mono-(2-hydroxyethyl) terephthalate hydrolase (MHETase) activity, more specifically to a polypeptide comprising an amino acid sequence that (i) has at least 70% sequence identity to SEQ ID NO:1 and (ii) differs from SEQ ID NO:1 by an a...

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Hauptverfasser: VONGSOUTHI, Vanessa, SAUNDERS, Jake Wesley, JACKSON, Colin John, SPENCE, Matthew, DAMRY, Adam Michael
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present disclosure relates generally to a polypeptide having mono-(2-hydroxyethyl) terephthalate hydrolase (MHETase) activity, more specifically to a polypeptide comprising an amino acid sequence that (i) has at least 70% sequence identity to SEQ ID NO:1 and (ii) differs from SEQ ID NO:1 by an amino acid substitution at one or more positions selected from the group consisting of positions that correspond to amino acid positions 156 to 396, 398 to 410 and 425 to 603 of SEQ ID NO:1.