MUTATED HOST CELLS WITH REDUCED CELL MOTILITY

The present invention relates to mutated bacterial host cells, said host cells producing a polypeptide of interest and having at least one disrupted flagellum gene, and to nucleic acid constructs and vectors encoding at least one flagellum polypeptide with reduced or eliminated activity as well as t...

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Bibliographische Detailangaben
Hauptverfasser: KALLEHAUGE, Thomas, Krogh, VINTHER, Jeppe, FEHLER, Annaleigh, Ohrt, GEISSLER, Adrian, Sven, GORODKIN, Jan
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to mutated bacterial host cells, said host cells producing a polypeptide of interest and having at least one disrupted flagellum gene, and to nucleic acid constructs and vectors encoding at least one flagellum polypeptide with reduced or eliminated activity as well as to methods of producing one or more polypeptide of interest in said host cells.