STABLE AQUEOUS BUFFER FREE FORMULATION OF AN INTEGRIN ANTIBODY

The present invention discloses a buffer free formulation of high concentration α4β7 antibody, comprising α4β7 antibody, water, and surfactant, and stabilized at a pH of 6.0-6.5. The disclosed antibody formulations are liquid formulations and can be lyophilized. Further, the said formulations are al...

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Bibliographische Detailangaben
Hauptverfasser:	GHOSH, Shrija, PAKHALE, Swapnil Vasudeo, JAYARAMAN, Murali, SAHA, Ananya
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention discloses a buffer free formulation of high concentration α4β7 antibody, comprising α4β7 antibody, water, and surfactant, and stabilized at a pH of 6.0-6.5. The disclosed antibody formulations are liquid formulations and can be lyophilized. Further, the said formulations are also suitable for different mode of administration such as subcutaneous/intravenous, for therapeutic use.