INHALABLE POWDER COMPRISING VORICONAZOLE IN CRYSTALLINE FORM

INHALABLE POWDER COMPRISING VORICONAZOLE IN CRYSTALLINE FORM

The present invention relates to a dry powder composition for inhalation use obtained by spray drying, comprising voriconazole, or a pharmaceutically active salt thereof, in substantially crystalline form, in an amount greater than 50% by weight with respect to the total amount of the powder. Said p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ZANELLOTTI, Laura, MAGGI, Loretta, CAPONETTI, Giovanni, CASTEGINI, Franco, NICOSIA, Valentina, FAIELLA, Gianluigi, MAGI, Nadia
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention relates to a dry powder composition for inhalation use obtained by spray drying, comprising voriconazole, or a pharmaceutically active salt thereof, in substantially crystalline form, in an amount greater than 50% by weight with respect to the total amount of the powder. Said powder has a respirable fraction (FPF) greater than 50%, an X90 lower than 6 μm and an MMAD lower than 5 μm.