NOVEL PAR-2 INHIBITORS

The present invention provides novel compounds of formula (I) and pharmaceutical compositions containing these compounds. The compounds of formula (I) can act as PAR-2 inhibitors, which renders these compounds highly advantageous for use in therapy, particularly in the treatment or prevention of pai...

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Bibliographische Detailangaben
Hauptverfasser: BLAYO, Anne-Laure, BARRÉ, Anaïs, FER, Mickaël, SCHANN, Stephan, RUGERI, Baptiste, MAYER, Stanislas, MICHAUT, Mathieu, HOMMET, Gaël
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention provides novel compounds of formula (I) and pharmaceutical compositions containing these compounds. The compounds of formula (I) can act as PAR-2 inhibitors, which renders these compounds highly advantageous for use in therapy, particularly in the treatment or prevention of pain, an autoimmune disorder, an autoinflammatory disorder, an inflammatory disorder, a central nervous system disorder, spinal cord injury, a metabolic disorder, a gastrointestinal disorder, a cardiovascular disorder, a fibrotic disorder, a respiratory disorder, a skin disorder, an allergic disorder, or cancer.