ANTI-IDIOTYPIC ANTIBODIES DIRECTED TO THE ANTIGEN-BINDING PORTION OF AN BCMA-BINDING MOLECULE

ANTI-IDIOTYPIC ANTIBODIES DIRECTED TO THE ANTIGEN-BINDING PORTION OF AN BCMA-BINDING MOLECULE

Isolated antigen binding molecules that specifically bind to a BCMA binding molecule are provided. The antigen binding molecules may be used in the methods provided herein. Specifically, monoclonal anti-idiotypic antibodies are provided which bind to the antigen-binding portion of a BCMA-binding mol...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: WILTZIUS, Jed J. W, SIEVERS, Stuart A
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
TESTING
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Beschreibung
Zusammenfassung:Isolated antigen binding molecules that specifically bind to a BCMA binding molecule are provided. The antigen binding molecules may be used in the methods provided herein. Specifically, monoclonal anti-idiotypic antibodies are provided which bind to the antigen-binding portion of a BCMA-binding molecule, in particular of anti-BCMA CARs.