MONOCLONAL ANTIBODY-BASED BIOSENSOR FOR POINT-OF-CARE DETECTION OF TYPE III SECRETION SYSTEM EXPRESSING PATHOGENS

The present disclosure relates to a biosensor chip device usable for identifying and/or quantifying a target in a sample by electrochemical impedance spectroscopy (EIS) analysis. The biosensor chip device disclosed herein comprises a plurality of electrodes connectable to at least one electronic dev...

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Bibliographische Detailangaben
Hauptverfasser:	SAL-MAN, Neta, WINE, Yariv, EVEN, Dan, GERSHBERG, Jenia, HILLMAN, Yaron, LUSTIGER, Dan, BRAVERMAN, Dor, ASHUR, Idan, VERNICK, Sefi
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS PROCESSES USING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present disclosure relates to a biosensor chip device usable for identifying and/or quantifying a target in a sample by electrochemical impedance spectroscopy (EIS) analysis. The biosensor chip device disclosed herein comprises a plurality of electrodes connectable to at least one electronic device, wherein, at least one of the electrodes is a working electrode connected directly or indirectly to at least one target binding site and/or moiety. It should be noted that the target binding site and/or moiety specifically binds the at least one target or any component thereof. Still further, in some embodiments, the plurality of electrodes is configured for electrochemical impedance spectroscopy (EIS) analysis of the sample. More specifically, the invention relates to monoclonal-antibody-based biosensor chip, devices, kits and diagnostic methods for detection of pathogens expressing Type III secretion system (T3SS) in a sample.