TREATMENT FOR MESOTHELIOMA THROUGH ADMINISTRATION OF ANTI-B7-H3 ANTIBODY-DRUG CONJUGATE

A therapeutic agent for mesothelioma comprising, as an active component, an anti-B7-H3 antibody-drug conjugate in which a drug-linker represented by the following formula,wherein A represents a connecting position to an anti-B7-H3 antibody; is conjugated to the anti-B7-H3 antibody via a thioether bo...

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Bibliographische Detailangaben
1. Verfasser:	YAMATO Michiko
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A therapeutic agent for mesothelioma comprising, as an active component, an anti-B7-H3 antibody-drug conjugate in which a drug-linker represented by the following formula,wherein A represents a connecting position to an anti-B7-H3 antibody; is conjugated to the anti-B7-H3 antibody via a thioether bond, and/or a method of treatment for mesothelioma, comprising administering the anti-B7-H3 antibody-drug conjugate to a subject in need of treatment for mesothelioma.