CATALYTIC SEQUENCE BASED METHODS OF TREATING OR PREVENTING BACTERIAL INFECTIONS

An oligonucleotide is provided. The oligonucleotide comprising a nucleic acid sequence of at least one DNAzyme, the DNAzyme being capable of silencing at least one target gene of a bacteria to thereby render the bacteria susceptible to antibiotic treatment.

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Bibliographische Detailangaben
Hauptverfasser: ROSENBERG, Alexander, LEVY-ZAMIR, Adva, HOROWITZ, Almogit, SHAPIRO, Anastasia, KOLODKIN-GAL, Ilana, ITTAH, Shmulik, GILLIS, Ella, KRIEGER, Gat, BACHELET, Ido, OSHRI, Ron
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:An oligonucleotide is provided. The oligonucleotide comprising a nucleic acid sequence of at least one DNAzyme, the DNAzyme being capable of silencing at least one target gene of a bacteria to thereby render the bacteria susceptible to antibiotic treatment.