MACROCYCLIC UREA OREXIN RECEPTOR AGONISTS

The present invention is directed to macrocyclic urea compounds which are agonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin rec...

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Bibliographische Detailangaben
Hauptverfasser:	KERN, Jeffrey, C, HURZY, Danielle, M, MANLEY, Peter, J, XIAO, Dong, RADA, Vanessa, L, ARMACOST, Kira, A, RUDD, Michael, T, CHIRIAC, Maria Irina, LIU, Jian, STUMP, Craig, A, WU, Zhe
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention is directed to macrocyclic urea compounds which are agonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which orexin receptors are involved.