CANCER THERAPY USING A COMBINATION OF CDK7 INHIBITOR WITH AN ANTI-MICROTUBULE AGENT

The present invention provides a combination of a substituted heterocyclyl derivative of formula (I) or a pharmaceutically acceptable salt thereof which is a CDK7 inhibitor along with an anti-microtubule agent or prodrug thereof, and a method of treating or preventing cancer in a subject, comprising...

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Bibliographische Detailangaben
Hauptverfasser:	NARAYANAN, Kishore, PODDUTOORI, Ramulu, KUMAR, Akhil
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides a combination of a substituted heterocyclyl derivative of formula (I) or a pharmaceutically acceptable salt thereof which is a CDK7 inhibitor along with an anti-microtubule agent or prodrug thereof, and a method of treating or preventing cancer in a subject, comprising administering to the subject a compound of formula (I) conjointly with the anti-microtubule agent.