INHIBITORS OF THE MENIN-MLL INTERACTION

The present invention is directed to inhibitors of the interaction of menin with MLL and MLL fusion proteins, pharmaceutical compositions containing the same, and their use in the treatment of cancer and other diseases mediated by the menin-MLL interaction.

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Bibliographische Detailangaben
Hauptverfasser: DONG, Chengguo, LOTESTA, Stephen D, CACATIAN, Salvacion, ZHUANG, Linghang, JIA, Lanqi, CLAREMON, David A, VENKATRAMAN, Shankar, FAN, Yi, ZHENG, Yajun, YUAN, Jing, SINGH, Suresh B
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention is directed to inhibitors of the interaction of menin with MLL and MLL fusion proteins, pharmaceutical compositions containing the same, and their use in the treatment of cancer and other diseases mediated by the menin-MLL interaction.