PHOSPHAPHENALENE-GOLD(I) COMPLEXES AS CHEMOTHERAPEUTIC AGENTS AGAINST GLIOBLASTOMA

Glioblastoma is one of the most lethal brain tumors. Difficulties for the treatment of glioblastoma involve, among others, the sensitivity of the brain to drugs, the limited brain penetration of chemotherapeutic agents and the resistance of tumor cells to conventional therapies. Provided are specifi...

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Hauptverfasser:	RÖSCH, Saskia, HEROLD-MENDE, Christel, FERMI, Valentina, ROMERO-NIETO, Carlos
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Glioblastoma is one of the most lethal brain tumors. Difficulties for the treatment of glioblastoma involve, among others, the sensitivity of the brain to drugs, the limited brain penetration of chemotherapeutic agents and the resistance of tumor cells to conventional therapies. Provided are specific phosphaphenalene-gold (I) complexes for use as a medicament, especially in the treatment of brain cancer such as glioblastoma, a pharmaceutical composition and a kit comprising such complex.