ORGANOID RECOMBINATION

Disclosed herein are organoid compositions having heterogeneous combinations of epithelial and mesenchymal components, and methods of making the same by dissociating and recombining the epithelial and mesenchymal components from different sources. These epithelial and mesenchymal components can be d...

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Bibliographische Detailangaben
Hauptverfasser:	BROWN, Nicole, SINGH, Akaljot, SUNDARAM, Nambirajan, VALES, Simon, HELMRATH, Michael, A
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Disclosed herein are organoid compositions having heterogeneous combinations of epithelial and mesenchymal components, and methods of making the same by dissociating and recombining the epithelial and mesenchymal components from different sources. These epithelial and mesenchymal components can be derived from the same or different cell type or organoid type. These organoid compositions may exhibit advantageous properties, for example, enhanced in vivo engraftment.