CONJUGATE OF FUNCTIONAL POLYPEPTIDE VARIANT, AND USE THEREOF

The present application relates to a functional polypeptide variant-lasting protein conjugate. The functional polypeptide variant-lasting protein conjugate of the present application is prepared by an inverse electron-demand Diels-Alder (IEDDA) reaction using a tetrazine group. In addition, the pres...

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Bibliographische Detailangaben
Hauptverfasser:	JEON, Su Jung, SHIN, Sun Oh, KWON, Inchan, KIM, Hyeongseok, BAK, Dong Ho, YANG, Byungseop, CHO, Jeong Haeng, KIM, Hyun Woo
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present application relates to a functional polypeptide variant-lasting protein conjugate. The functional polypeptide variant-lasting protein conjugate of the present application is prepared by an inverse electron-demand Diels-Alder (IEDDA) reaction using a tetrazine group. In addition, the present application provides a functional polypeptide variant including a non-natural amino acid. The non-natural amino acid included in the functional polypeptide of the present application is characterized by including a tetrazine group or triazine group.