SOLUTE-PHASE ELECTROCHEMICAL APTAMER SENSORS FOR IMPROVED LONGEVITY AND SENSITIVITY

SOLUTE-PHASE ELECTROCHEMICAL APTAMER SENSORS FOR IMPROVED LONGEVITY AND SENSITIVITY

A device and method for detecting the presence of, or measuring the concentration or amount of, at least one analyte in a sample fluid. The device 100 includes at least one electrode 150, a sensor fluid 18, a plurality of aptamers freely diffusing in the sensor fluid, and a plurality of redox tags a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HEIKENFELD, Jason, YUAN, Yuchan
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
DIAGNOSIS
HUMAN NECESSITIES
HYGIENE
IDENTIFICATION
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
PHYSICS
SURGERY
TESTING
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Beschreibung
Zusammenfassung:A device and method for detecting the presence of, or measuring the concentration or amount of, at least one analyte in a sample fluid. The device 100 includes at least one electrode 150, a sensor fluid 18, a plurality of aptamers freely diffusing in the sensor fluid, and a plurality of redox tags associated with at least a subset of aptamers of the plurality of aptamers. The sensor fluid is capable of having a sample fluid 14 introduced thereinto, and the detection or measurement of any analyte may occur through a change in electron transfer from at least one redox tag of the plurality of redox tags.