THERAPEUTIC WINDOW FOR TREATMENT OF ISCHEMIA BY VAGUS NERVE STIMULATION

Closed-loop stimulation of the Vagus nerve in response to a detected myocardial ischemia state within a therapeutic window can mitigate or reverse effects of the ischemia. This window is between 0 and 50 seconds of the onset of ischemia, before the myocardial ischemia reaches a statistically signifi...

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Hauptverfasser: GANZER, Patrick, WEBER, Doug, LOEIAN, Seyed Masoud, FRIEDENBERG, David A
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Closed-loop stimulation of the Vagus nerve in response to a detected myocardial ischemia state within a therapeutic window can mitigate or reverse effects of the ischemia. This window is between 0 and 50 seconds of the onset of ischemia, before the myocardial ischemia reaches a statistically significant evolution level. A properly trained machine learning system such as a long short-term memory system can be used to analyze cardiovascular features and detect myocardial ischemia within the therapeutic window.