METHODS OF PRODUCING EXTRACELLULAR VESICLES

The present disclosure relates to extracellular vesicles (EVs), e.g., exosomes, which can be rapidly modified to comprise an antigen of interest, and the uses of such EVs as vaccines for the treatment of wide range of diseases or disorders. Also provided herein are methods for preparing and manufact...

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Bibliographische Detailangaben
Hauptverfasser: NOYES, Aaron, ZHANG, Eric, DOOLEY, Kevin P, SOOS, Tim
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present disclosure relates to extracellular vesicles (EVs), e.g., exosomes, which can be rapidly modified to comprise an antigen of interest, and the uses of such EVs as vaccines for the treatment of wide range of diseases or disorders. Also provided herein are methods for preparing and manufacturing such EVs for use as vaccines.