KRAS G12D INHIBITORS

The present invention relates to compounds that inhibit KRas G12D. In particular, the present invention relates to compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor.

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Bibliographische Detailangaben
Hauptverfasser: DAHLKE, Joshua Ryan, HILTON, Michael Christopher, PAJK, Spencer, SAVECHENKOV, Pavel Yu, RODRIGUEZ, Martha E, ALLEN, Shelley, NGUYEN, Phong, CHICARELLI, Mark Joseph, DAI, Donghua, FELL, Jay Bradford, MEJIA, Macedonio Junior, MARX, Matthew Arnold, WANG, Xiaolun, FISCHER John, Peter, KAHN, Dean Russell, TANG, Tony Pisal
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to compounds that inhibit KRas G12D. In particular, the present invention relates to compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor.