NEBULIZER AND NEBULIZED ANTI-VIRALS

An antiviral medication which may be an aerosolizable formulation having a pharmaceutically active anti-viral compound present as a neutral compound selected from the group of free acid, free base, water insoluble salt and water insoluble ion pair); an excipient capable of forming a liquid complex w...

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Bibliographische Detailangaben
Hauptverfasser: FACTOR, Andrey, KELM, Gary Robert, GRIFFOR, Edward Ronald, KING, Donald O
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:An antiviral medication which may be an aerosolizable formulation having a pharmaceutically active anti-viral compound present as a neutral compound selected from the group of free acid, free base, water insoluble salt and water insoluble ion pair); an excipient capable of forming a liquid complex with the pharmaceutically active anti-viral compound; and a polymeric surfactant suitable for pulmonary administration. A nebulizer to deliver the antiviral medication may have a compressed air chamber in communication with a medication chamber, the communication sealed by a spring valve in a rested state. A nebulizer chamber is in communication with the medication chamber, the nebulizer chamber having a pressure release orifice to deliver a stream the nebulized particle stream to the facemask and a continuously variable nebulizing pressure feed at the pressure release orifice.