MOLECULES WITH SOLUBILITY TAG AND RELATED METHODS

MOLECULES WITH SOLUBILITY TAG AND RELATED METHODS

The present disclosure relates to molecules comprising a targeting moiety, at least one payload wherein said at least one payload is a therapeutic agent or a detectable lable, a linker/linkers covalently linking said payload/payloads and said targeting moiety, and at least one solubility tag, wherei...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CRASSIER, Helene, VON HAGEN, Joerg, DEUTSCH, Carl, KELLY, Sven, RICHTER-SANDER, Ulrike, KORPUS, Christoph
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present disclosure relates to molecules comprising a targeting moiety, at least one payload wherein said at least one payload is a therapeutic agent or a detectable lable, a linker/linkers covalently linking said payload/payloads and said targeting moiety, and at least one solubility tag, wherein said solubility tag comprises at least 3 and up to 12 monosaccharide units.