HYDROGEL FORMULATION COMPRISING ZEBULARINE AND RETIONIC ACID
A pharmaceutical composition comprising two hydrogel formulations with biologically active substances for simultaneous use, one mixture of which comprises not less than 60 and not more than 240 mg of zebularine added to 1 ml of sodium alginate hydrogel, and the other mixture of which comprises not l...
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creator | Sass, Piotr Baczynski-Keller, Jakub Sachadyn, Pawel Slonimska, Paulina Dzierzynska, Maria Pikula, Michal Deptula, Milena Skowron, Piotr Sawicka, Justyna Kaminska, Jolanta Rodziewicz-Motowidlo, Sylwia Platek, Rafal Sosnowski, Pawel |
description | A pharmaceutical composition comprising two hydrogel formulations with biologically active substances for simultaneous use, one mixture of which comprises not less than 60 and not more than 240 mg of zebularine added to 1 ml of sodium alginate hydrogel, and the other mixture of which comprises not less than 1 and not more than 4 mg of retinoic acid added to 1 ml of sodium alginate hydrogel, wherein the biologically active substances, i.e. zebularine and retinoic acid, release gradually from each formulation due to hydrogel biodegradation, which allows their combined action to be used to stimulate complex tissue regeneration. |
format | Patent |
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subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
title | HYDROGEL FORMULATION COMPRISING ZEBULARINE AND RETIONIC ACID |
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