ANTI-TIGIT ANTIBODY AND METHODS OF USE THEREOF

ANTI-TIGIT ANTIBODY AND METHODS OF USE THEREOF

The present disclosure provides antibodies that specifically bind to TIGIT. The antibodies find use in a variety of treatment, diagnostic, and monitoring applications, which are also described. For example, the antibody may be used to treat a patient for cancer, particularly a patient is also being...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: IFFLAND, Christel, IZQUIERDO, Shelley, COLLARINI, Ellen, HARRIMAN, William Don
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:The present disclosure provides antibodies that specifically bind to TIGIT. The antibodies find use in a variety of treatment, diagnostic, and monitoring applications, which are also described. For example, the antibody may be used to treat a patient for cancer, particularly a patient is also being treated or has been treated with an immune checkpoint inhibitor, e.g., a PD-1/PD-L1 inhibitor.