KRAS G12D INHIBITORS

The present invention relates to compounds that inhibit KRas G12D. In particular, the present invention relates to compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor.

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Bibliographische Detailangaben
Hauptverfasser: LAWSON, John David, FISCHER, John Peter, DAHLKE, Joshua Ryan, HILTON, Michael Christopher, BARBOUR, Patrick Michael, ALLEN, Shelley, MEJIA, Macedonio, Junior, BLAKE, James Francis, O'LEARY, Jacob Matthew, DAI, Donghua, HASSANIEN, Sherif Hosam, FELL, Jay Bradford, MARX, Matthew Arnold, WANG, Xiaolun, TANG, Tony Pisal
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to compounds that inhibit KRas G12D. In particular, the present invention relates to compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor.