INTERMEDIATES AND PROCESS FOR PREPARING L-DOPA DIPHOSPHATE

The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dop...

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Bibliographische Detailangaben
Hauptverfasser:	MAYER, Peter T, ZHANG, Geoff G, DEMPAH, Kassibla E, KRABBE, Scott W, KYM, Philip R, HUTERS, Alexander D, MILLER, Christopher P, HENRY, Rodger F, HUANG, Ye, MACKEY, Sean E, CARDINAL-DAVID, Benoit, ENRIGHT, Brian P, KLIX, Russell C, LAO, Yanbin, LOU, Xiaochun, MATULENKO, Mark A, STELLA, Valentino J, HO, Raimundo, WANG, Zhi, STAMBULI, James, CHAN, Vincent S, VOIGHT, Eric A
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.