A WHOLE SLIDE IMAGING METHOD FOR A MICROSCOPE

A method is provided for operating a microscope scanner 1 comprising a line scanner 3. Pre-scan data is generated for a target 6 comprising a sample, wherein generating the pre-scan data comprises: obtaining a pre-scan image of the target 6 from a pre-scan; and identifying one or more sample-containing regions 24 and one or more sample-free regions 26 of the target 6 from the pre-scan image. An imaging scan is then performed of a scanning region of the target 6 including the one or more sample-containing regions 24 and the one or more sample-free regions 26. The scanning speed of the line scanner 3 is adjusted along the image scan path based on the pre-scan data so that the target 6 is imaged at a higher scanning speed within the one or more sample-free regions 26 than in the one or more sample-containing regions 24.